The tenth Doctor stated to Wilfred that even though he would regenerate it would still feel like dying because he had experienced so much as that incarnation.

At the time he was talking to Wilf, of course, he didn't know what was going to happen to him but he did know (and said) that he could be killed outright, then went on to say (as noted above) that even if he regenerated it would still feel like dying.

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