No. We've seen her damaged in, for example, "The End of Time" Part 2. We've also seen her blown up in "The Pandorica Opens", although she was restored in "The Big Bang". The destruction of the TARDIS also appeared to be a very real possibility in "Journey's End". And "the Doctor's Wife" is all about the destruction of TARDISes by House, and we see many destroyed/disassembled TARDISes.